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Common side effects include bone marrow suppression and vomiting. Azathioprine was first made in In the United States, it is approved by the Food and Drug Administration FDA for use in kidney transplantation from human donors, and for rheumatoid arthritis. Azathioprine is used to prevent rejections of kidney or liver allografts, usually in conjunction with other therapies including corticosteroids, other immunosuppressants, and local radiation therapy. Being a disease-modifying antirheumatic drug DMARD, azathioprine has been used for the management of the signs and symptoms of adult rheumatoid arthritis. It may also be used to prevent flares in those with ulcerative colitis.
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