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Acyclovir and Valacyclovir are similar drugs used to treat herpes infections. They are so similar that valacyclovir is considered a prodrug of acyclovir. In other words, valacyclovir is converted into acyclovir in the body. They work by blocking the virus from multiplying. Although acyclovir and valacyclovir are identical drugs, there are some slight differences between the two. It works as a purine analogue to block activity from the herpes simplex virus HSV-1 and HSV-2 and varicella-zoster virus.
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