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Metrics details. Cardiac toxicity is one of the life-threatening complications of cancer therapy. Systemic anticancer treatments may exert their own toxic effects or can aggravate adverse effects of other drugs. We report a case of cyclophosphamide-induced cardiotoxicity in a patient with normal cardiac functions before chemotherapy. A year-old Caucasian woman with a mediastinal mass diagnosed with Burkitt lymphoma underwent chemotherapy with rituximab-hyperfractionated-cyclophosphamide-vincristine-doxorubicin-dexamethasone. On the seventh day of chemotherapy, she developed dyspnea.

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Powder for injection. High: when cytoxan 2mg of with combined with cyclophosphamide in breast cancer patients Moderate: when used alone. Cytoxan 2mg of elevated levels of metabolites of cyclophosphamide have been observed in patients with renal failure, cyclophosphamide may induce tumor- lysis syndrome and hyperuricemia in patients with rapidly growing tumors? Selinexor is indicated in combination with dexamethasone for adults with relapsed or refractory MM who have received at least 4 prior therapies and whose disease is refractory to at least 2 proteasome inhibitors, increased clinical toxicity in such patients has not been demonstrated, Sc. AMA Council Report.


Systemic lupus erythematosus SLE is an autoimmune disease that may affect nearly any organ system in the human body. The autoimmunity present in patients with SLE causes local inflammation and tissue damage, and it may present with a variety of symptoms depending on the organ system involved.


Lina (taken for 3 to 4 years) 01.03.2018

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Each tablet contains cyclophosphamide monohydrate equivalent to 50 mg anhydrous cyclophosphamide. Cyclophosphamide is a cytotoxic drug for the treatment of malignant disease in adults and children.


Theresa (taken for 2 to 6 years) 21.08.2018

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The mechanism of action is thought to involve cross-linking of tumor cell DNA. The unchanged drug has an elimination half-life of 3 to 12 hours. Several cytotoxic and noncytotoxic metabolites have been identified in urine and in plasma.


Benedikt (taken for 1 to 7 years) 21.10.2016

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