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Because there is not a single, specific cause of fibromyalgia and the symptoms can vary from patient to patient, choosing an effective treatment can be challenging. Experts say the best, overall strategy includes medications and nondrug therapies, such as exercise, counseling, and stress relief. The medications used to treat fibromyalgia include antidepressants amitriptyline, nortriptyline, fluoxetine, paroxetine, https://clark.com duloxetine, milnacipran, a few anti-seizure medications gabapentin, pregabalin, and a muscle relaxant cyclobenzaprine. There is no clear evidence that one drug is better than another, and all of them probably lose their benefit over time. Each drug differs in the risks it poses to you. All antidepressants should be used with caution in those with a history of suicide attempt or who are at risk of suicide, especially in people 25 years old or younger. Amitriptyline, cyclobenzaprine, gabapentin, and pregabalin all cause increased sedation and should be used with caution in the elderly. See here for the full report on drugs used to treat fibromyalgia. All of these medications have been on the market for 15 years or more and have been widely used. They are all available as inexpensive generics and are at least as effective and safe as the other fibromyalgia medications.
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Nortriptyline is the only other antidepressant that has demonstrated efficacy in improving smoking cessation outcome Hughes et al. From: International Encyclopedia of Public Health, Nortriptyline, a tricyclic antidepressant with a half-life of 37 hours, is the active metabolite of amitriptyline. With other infants only minute amounts of a hydroxy-metabolite were found. Nortriptyline can be prescribed for appropriate indications during breastfeeding. Nortriptyline, half-life 37 hours, is the active metabolite of amitriptyline.
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A tricyclic antidepressant with a relatively short latency period. It has almost no sedative effect. In combination with amitriptyline it is used for depressions that occurred during treatment with reserpine. In combination with neuroleptics, it is used in the treatment of depression that developed during treatment of schizophrenic psychoses. It is used in the treatment of some major depressive disorder and nocturnal enuresis bedwetting in children.
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Nortriptyline hydrochloride, the congress metabolite of amitriptyline, is a tricyclic antidepressant TCA. A governmentally-recognized ID which uniquely identifies the product within its regulatory agency.
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Adults: The usual adult dose is 25mg three or four times daily. Dosage should begin at a low level 50mg once daily or 25mg times daily. Doses above mg per day are not recommended. Lower than usual dosages are recommended for elderly patients. Lower dosages are also recommended for outpatients than https://www.webmd.com for hospitalised patients who will be under close supervision.
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