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What major contribution have advanced drug delivery systems made to anti-inflammatory drug therapy? Discuss the importance of the developing world as a market for advanced drug delivery systems pamelor 25mg low price. Also, rate-control and drug targeting are treated as two separate issues in this book and are dealt with in detail in Chapters 4 and 5 respectively. If the drug concentration gradient remains constant, for example where solid drug particles are present and constant dissolution maintains the concentration of the drug in solution, the rate of drug release does not vary with time and zero- order controlled release is attained see Chapter 4 and Figure 4. This is because as the drug molecules at the surface of the device are released, those in the centre of the device have to migrate longer distances to be released, which takes a longer time. This increased diffusion time results in a decrease in the release rate from the device with time.
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