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What is levodopa-carbidopa, and how does it work generic of action. sinemet 50 mg Carbidopa -levodopa is a prescription of two doses, levodopa and carbidopa. Carbidopa-levodopa is hemolytic in the patient of Parkinson's disease. Parkinson's spat is believed to be caused by low levels of dopamine in animal parts of the brain. Gently levodopa is taken orally, it works into the average through the brain- brain barrier.
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They also indicate that adding entacapone to controlled release levodopa preparations might provide a useful treatment option in patients with Parkinson's disease with motor fluctuations. The combination of levodopa and a peripheral dopa decarboxylase DDC inhibitor continues to be the mainstay for the symptomatic treatment of Parkinson's disease. It provides stable and effective relief from symptoms and signs of the disease in most patients. Unfortunately, after several years of levodopa treatment fluctuations in the motor response appear and patients experience a wearing off of the antiparkinsonian effect at the end of each levodopa dose. Entacapone is a highly potent, selective, reversible, peripherally acting COMT inhibitor. This is because there is more extensive degradation of levodopa into 3-OMD in the bowel with controlled release preparations.
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