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Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. A governmentally-recognized ID which uniquely identifies the product within its regulatory market. For the treatment of patients with metastatic breast cancer resistant to both paclitaxel and an anthracycline-containing chemotherapy regimen. The use or capecitabine in combination regimens for advanced gastric cancer is currently being investigated. Capecitabine is a fluoropyrimidine carbamate with antineoplastic activity indicated for the treatment of metastatic breast cancer and colon cancer. It is an orally administered systemic prodrug that has little pharmacologic activity until it is converted to fluorouracil by enzymes that are expressed in higher concentrations in many tumors. Capecitabine is a prodrug that is selectively tumour-activated to its cytotoxic moiety, fluorouracil, by thymidine phosphorylase, an enzyme found in higher concentrations in many tumors compared to normal tissues or plasma.
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Twelves has acted as an ad hoc consultant to Roche and has also received honoraria for speaking and served on advisory committees for Roche. Hornberger has a consulting arrangement with federal agencies Veterans Administration, U. No limitations on publication were imposed. The authors made the final decisions on all aspects of the current article. Data on survival time and medical care resource use were prospectively collected in the trial.
I commend Chairman Gregg and Senator Kennedy for bringing this important issue before the Committee, and I look forward to working with them to ensure the safe importation of prescription drugs from Canada and other industrialized nations. Today U. This ishighway robbery of our most vulnerable citizens and it must be stopped. Drug manufacturers are using American consumers to subsidize lower prescription drugsprices in countries such as Canada. They are forced to sell their products at lower prices in othercountries and try to re-coup their research and development costs by making Americans pay higherprices for the same products. If importation is legalized in the U.
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